Analytical Genomics

Phylogeny matters in residue coevolution! try your favorite protein with iBIS2Analyzer. It works for conserved proteins like viral ones. See our last article in Nucleic Acids Research.
See also the press release by Sorbonne Université (in french).

See the new highlight on ActuIA for our work on protein functional classification.

A novel computational approach to explore and classify functional diversity in genomic sequences. See the new article appeared in Molecular Biology and Evolution from the Analytical Genomics team.

Read the press release at Sorbonne Université and the CNRS

A press release from the ANRS on our eLife article

We provided crucial insights to the molecular mechanism through which HBV infects cells. A fusion peptide in preS1 and the human protein-disulfide isomerase ERp57 are involved in HBV membrane fusion process.

Link to the article

Elodie Laine, from the Analytical Genomics team, is co-organizig two events addressing the new challenges in structural biology and bioinformatics, with a particular focus on Artificial Intelligence and Integrative Modeling.

— Structural Bioinformatics Mini-Symposium @JOBIM

It will take place on Thursday 8th July, in the afternoon, on air. You need to be registered to JOBIM 2021 to attend! The program can be found here: https://research.pasteur.fr/en/event/jobim-mini-symposium-integrative-structural-modeling-in-the-era-of-big-data-and-artificial-intelligence/
— New directions of AI in structural biology Workshop @CIRM

A small in-person gathering intended to mix « structuralists » and « machine learnists » and to foster new ideas and projects. There is still room, so please consider applying through: https://conferences.cirm-math.fr/2700.html.

A global study of 60 cities' microbes finds each has a signature microbial fingerprint. The project provides a great way to communicate about the invisible world of commensal microorganisms. Members at the LCQB, L3 and M1 Sorbonne’s students involved in our Bioinformatics courses and colleagues from other Sorbonne departments contributed to the collect of the samples for the Paris area. The article just appeared in Cell.

Our analysis of "soft disorder" makes the cover of the PLoS Computational Biology January issue.

Link to the paper
 

Our paper "COVTree: Coevolution in OVerlapped sequences by Tree analysis server" has been cited among the papers founded by ANRS in the context of "Journée mondiale contre l’hépatite 2020 : l’ANRS toujours engagée"

ANRS communicates today on our new webserver COVTree, designed to predict coevolving residues in overlapping genes and to detect mirrored coevolution.

Link to the article